Recognition of fluoride anions at low ppm level inside living cells and from fluorosis affected tooth and saliva samples

A simple Schiff base chemosensor 2-((2-(2,4-dinitro phenyl)hydrazono)methyl)-4-nitrophenol ( L ) has been developed as a colorimetric and fluorimetric ‘ turn on ’ sensor for fluoride (F − ). F − recognition at ppm levels from mouth rinses and a toothpaste water solution has been successful. Signific...

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Published inRSC advances Vol. 5; no. 35; pp. 27387 - 27392
Main Authors Ghosh, Pritam, Roy, Biswajit Gopal, Mukhopadhyay, Subhra Kanti, Banerjee, Priyabrata
Format Journal Article
LanguageEnglish
Published 01.01.2015
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Summary:A simple Schiff base chemosensor 2-((2-(2,4-dinitro phenyl)hydrazono)methyl)-4-nitrophenol ( L ) has been developed as a colorimetric and fluorimetric ‘ turn on ’ sensor for fluoride (F − ). F − recognition at ppm levels from mouth rinses and a toothpaste water solution has been successful. Significantly, L can detect F − from fluorosis affected tooth and saliva samples by similar colorimetric changes. A test kit for F − detection from a DMSO–water (1 : 1) mixture is also engineered. Intracellular F − from pollen grains of Techoma stans and Candida albicans (a diploid fungus), grown in 10 −6 (M) F − contaminated water has been successfully detected under a fluorescence microscope.
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ISSN:2046-2069
2046-2069
DOI:10.1039/C5RA01720C