Nylon nanofibrous membrane for mediated glucose biosensing

This work illustrates how polyamide nanofibrous membranes, prepared by the electrospinning process, can act as a new type of biosensor element. The sensing unit is based on a glassy carbon electrode coated with polyamide nanofibrous membranes, in which glucose oxidase is covalently tethered. The wor...

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Published inSensors and actuators. B, Chemical Vol. 145; no. 1; pp. 394 - 397
Main Authors Scampicchio, Matteo, Arecchi, Alessandra, Lawrence, Nathan S., Mannino, Saverio
Format Journal Article
LanguageEnglish
Published Elsevier B.V 04.03.2010
Subjects
Biosensor
Electrospinning
Food
Glucose
Nanofibers
Nylon membrane
Electrospinning
Nylon membrane
Glucose
Nanofibers
Biosensor
Food
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Summary:This work illustrates how polyamide nanofibrous membranes, prepared by the electrospinning process, can act as a new type of biosensor element. The sensing unit is based on a glassy carbon electrode coated with polyamide nanofibrous membranes, in which glucose oxidase is covalently tethered. The work is carried out by means of transient electrochemical techniques, such as cyclic voltammetry and amperometry, in which ferrocene methanol was employed as mediator. The results show that nanofibrous membranes are an excellent support for the development of biosensors thanks to their high-surface to volume ratio, high porosity and permeability of the cosubstrate and minimal effect on both the biocatalytic kinetics and the selectivity of the biorecognition event. The optimization, characterization, and attractive performance of the nanofibrous biosensor are reported in connection with the detection of glucose in a variety of food beverages.
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ISSN:0925-4005
1873-3077
DOI:10.1016/j.snb.2009.12.042