Familial autoimmune myasthenia gravis
We describe a family with parental consanguinity and five of 10 siblings affected by late-onset autoimmune myasthenia gravis. We propose a genetic mechanism as a predisposing factor in this family. Our analysis excludes the major histocompatibility complex, the beta subunit of the acetylcholine rece...
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Published in | Neurology Vol. 44; no. 3 Pt 1; p. 551 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
United States
01.03.1994
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Subjects | |
Online Access | Get more information |
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Summary: | We describe a family with parental consanguinity and five of 10 siblings affected by late-onset autoimmune myasthenia gravis. We propose a genetic mechanism as a predisposing factor in this family. Our analysis excludes the major histocompatibility complex, the beta subunit of the acetylcholine receptor, and the T-cell receptor alpha and beta subunits as candidate genes for the disorder in this family. |
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ISSN: | 0028-3878 |
DOI: | 10.1212/WNL.44.3_Part_1.551 |