Very high pressure HPLC with 1 mm id columns

Theoretical calculations and experimental data indicate that very high pressure HPLC can be performed using 1 and 1.5 mm id columns, and contrary to previous beliefs, the frictional heating generated does not appear to be detrimental to the separation.

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Bibliographic Details
Published inAnalyst (London) Vol. 129; no. 6; pp. 503 - 504
Main Authors COLON, Luis A, CINTRON, José M, ANSPACH, Jason A, FERMIER, Adam M, SWINNEY, Kelly A
Format Journal Article
LanguageEnglish
Published Cambridge Royal Society of Chemistry 01.01.2004
Subjects
Analytical chemistry
Chemistry
Chromatographic methods and physical methods associated with chromatography
Chromatography, High Pressure Liquid - instrumentation
Chromatography, High Pressure Liquid - methods
Equipment Design
Exact sciences and technology
Hot Temperature
Other chromatographic methods
HPLC chromatography
Experimental data
High pressure
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Summary:Theoretical calculations and experimental data indicate that very high pressure HPLC can be performed using 1 and 1.5 mm id columns, and contrary to previous beliefs, the frictional heating generated does not appear to be detrimental to the separation.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0003-2654
1364-5528
DOI:10.1039/b405242k