Investigation of assay interference with microbiological determinations of chlortetracycline in feed grade and premix samples

Studies were initiated to determine whether tetracycline components such as tetracycline and 4-epichlortetracycline present in commercial feed grade chlorteracycline (CTC) products interfere with AOAC Method 967.39. These investigations confirmed that the microbiological result for feed grade concen...

Full description

Saved in:
Bibliographic Details
Published inJournal of AOAC International Vol. 80
Main Authors Webster G.K, Luigs E.S, Hearne L.A, Pomeroy M, Panozzo L.A, Bell J, Mustapha M.A
Format Journal Article
LanguageEnglish
Published 01.03.1997
Subjects
additif aux aliments des animaux
aditivos de piensos
analytical methods
bioassays
chemical composition
chromatographie
chromatography
composicion quimica
composition chimique
cromatografia
dosage biologique
ensayo biologico
feed additives
measurement
medicion
mesure
technique analytique
tecnicas analiticas
tetraciclina
tetracycline
tetracyclines
Online AccessGet more information

Cover

More Information
Summary:Studies were initiated to determine whether tetracycline components such as tetracycline and 4-epichlortetracycline present in commercial feed grade chlorteracycline (CTC) products interfere with AOAC Method 967.39. These investigations confirmed that the microbiological result for feed grade concentrates and premix products is not affected by the biomass matrix containing low levels of these other tetracycline components. Thus, the microbiological result can be directly correlated to the single CTC peak response in liquid chromatographic analytical procedures.
Bibliography:L70
L
ISSN:1060-3271
1944-7922
DOI:10.1093/jaoac/80.2.298