Androgen-associated hepatoma in a hemodialysis patient

A patient on hemodialysis treatment developed hepatocellular carcinoma (HCC) after long-term therapy with androgenic anabolic steroids. The tumor progressed very rapidly, and there was no evidence of regression despite discontinuation of the drug. In view of the evidence of an increased of malignanc...

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Bibliographic Details
Published inNephron (2015) Vol. 29; no. 5-6; p. 274
Main Authors Zevin, D, Turani, H, Cohen, A, Levi, J
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.1981
Subjects
Aged
Anemia - drug therapy
Carcinoma, Hepatocellular - chemically induced
Humans
Kidney Failure, Chronic - therapy
Liver Neoplasms - chemically induced
Male
Oxymetholone - adverse effects
Oxymetholone - therapeutic use
Renal Dialysis
Time Factors
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Summary:A patient on hemodialysis treatment developed hepatocellular carcinoma (HCC) after long-term therapy with androgenic anabolic steroids. The tumor progressed very rapidly, and there was no evidence of regression despite discontinuation of the drug. In view of the evidence of an increased of malignancy in patients with chronic uremia and hemodialysis, and of the higher frequency of HCC correlated to treatment with C17-alkylated anabolic steroids, it is necessary to further evaluate the efficiency of this treatment in the aforementioned group of patients.
ISSN:1660-8151
DOI:10.1159/000182388