Evaluation of breast tumor margins in vivo with intraoperative photoacoustic imaging

• Published in: Optics express Vol. 20; no. 8; pp. 8726 - 8731
• Main Authors: Xi, Lei, Grobmyer, Stephen R, Wu, Lei, Chen, Ruimin, Zhou, Guangyin, Gutwein, Luke G, Sun, Jingjing, Liao, Wenjun, Zhou, Qifa, Xie, Huikai, Jiang, Huabei
• Format: Journal Article
• Language: English
• Published: United States 09.04.2012
• Subjects: Animals; Breast Neoplasms - pathology; Breast Neoplasms - surgery; Disease Models, Animal; Equipment Design; Female; Humans; Imaging, Three-Dimensional; Intraoperative Care - instrumentation; Intraoperative Care - methods; Mice; Neoplasms, Experimental - pathology; Neoplasms, Experimental - surgery; Optical Phenomena; Photoacoustic Techniques - instrumentation; Photoacoustic Techniques - methods; Tomography, Optical - instrumentation; Tomography, Optical - methods

The use of photoacoustic effect is a promising approach for biomedical imaging in living tissues. Photoacoustic tomography (PAT) has been demonstrated to image breast cancer, brain vasculature, arthritis and seizure focus owing to its rich optical contrast and high resolution in a single imaging mod...