Noise suppressed optical diffraction tomography with autofocus correction

We propose a novel tomographic measurement approach that enables a noise suppressed characterization of microstructures. The idea of this work is based on a finding that coherent noise in the input phase data generates an artificial circular structure whose magnitude is the highest at the centre of...

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Bibliographic Details
Published inOptics express Vol. 22; no. 5; pp. 5731 - 5745
Main Authors Kostencka, Julianna, Kozacki, Tomasz, Dudek, Michał, Kujawińska, Małgorzata
Format Journal Article
LanguageEnglish
Published United States 10.03.2014
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Summary:We propose a novel tomographic measurement approach that enables a noise suppressed characterization of microstructures. The idea of this work is based on a finding that coherent noise in the input phase data generates an artificial circular structure whose magnitude is the highest at the centre of tomographic reconstruction. This method decreases the noise level by applying an unconventional tomographic measurement configuration with an object deliberately shifted with respect to the rotation axis. This enables a spatial separation between the reconstructed sample structure and the area of the largest refractive index perturbations. The input phase data defocusing that is a by-product of the introduced modification is numerically corrected with an automatic focus correction algorithm. The proposed method is validated with simulations and experimental measurements of an optical microtip.
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ISSN:1094-4087
1094-4087
DOI:10.1364/OE.22.005731