Prolonged fever as a presenting symptom in adrenal tumors

Four patients with adrenal tumors in whom prolonged fever was the foremost symptom are presented. Two of the patients had nonfunctional adrenocortical carcinoma, one had a pheochromocytoma without adrenergic hyperactivity, and in the fourth, an aldosteronoma was found. Only in 1 case was the tumor (...

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Bibliographic Details
Published inOncology Vol. 45; no. 1; p. 15
Main Authors Klausner, J M, Nakash, R, Inbar, M, Gutman, M, Lelcuk, S, Rozin, R R
Format Journal Article
LanguageEnglish
Published Switzerland 1988
Subjects
Adrenal Gland Neoplasms - diagnosis
Adrenal Gland Neoplasms - physiopathology
Aged
Female
Fever - etiology
Humans
Male
Middle Aged
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Summary:Four patients with adrenal tumors in whom prolonged fever was the foremost symptom are presented. Two of the patients had nonfunctional adrenocortical carcinoma, one had a pheochromocytoma without adrenergic hyperactivity, and in the fourth, an aldosteronoma was found. Only in 1 case was the tumor (pheochromocytoma) resectable and this patient became afebrile post surgery. A review of the literature revealed that fever is encountered in 6-10% of cases with adrenal tumors, sometimes as the first manifestation of disease. However, a survey of the large series of fever of unknown origin revealed no mention of adrenal tumors in that group of solid tumors which many cause prolonged fever.
ISSN:0030-2414
DOI:10.1159/000226522