Effect of acetylcysteine (Mucomyst) on epithelial wound healing

The rate of reepithelialization of the rabbit cornea, receiving isotonic NaCl solution and acetylcysteine (Mucomyst) solution at 10 and 20% concentrations, following a superficial epithelial ulcer was studied by fluorescein staining, photography and light microscopy. Acetylcysteine solution does not...

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Bibliographic Details
Published inOphthalmic research Vol. 14; no. 4; p. 241
Main Authors Petroutsos, G, Guimaraes, R, Giraud, J P, Renard, G, Pouliquen, Y
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.1982
Subjects
Acetylcysteine - pharmacology
Acetylcysteine - therapeutic use
Animals
Cornea - drug effects
Corneal Ulcer - drug therapy
Epithelium - drug effects
Female
Male
Rabbits
Wound Healing - drug effects
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Summary:The rate of reepithelialization of the rabbit cornea, receiving isotonic NaCl solution and acetylcysteine (Mucomyst) solution at 10 and 20% concentrations, following a superficial epithelial ulcer was studied by fluorescein staining, photography and light microscopy. Acetylcysteine solution does not seem to retard normal epithelial healing compared with control animals which received isotonic NaCl solution.
ISSN:0030-3747
DOI:10.1159/000265198