Selective solubilization of hemagglutinin and neuraminidase from influenza viruses
A novel approach is described for the isolation of hemagglutinin and neuraminidase from influenza viruses. In contrast to published procedures, the two glycoproteins are selectively solubilized, leaving an intact viral subparticle which contains lipid, RNA and non-glycoproteins. The pronounced diffe...
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Published in | Intervirology Vol. 5; no. 5; p. 260 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
Switzerland
01.01.1975
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Subjects | |
Online Access | Get more information |
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Summary: | A novel approach is described for the isolation of hemagglutinin and neuraminidase from influenza viruses. In contrast to published procedures, the two glycoproteins are selectively solubilized, leaving an intact viral subparticle which contains lipid, RNA and non-glycoproteins. The pronounced differences in size allow a simple separation of the solubilized proteins from the virus 'core'. |
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ISSN: | 0300-5526 |
DOI: | 10.1159/000149923 |