Clinical staging for cutaneous T-cell lymphoma

The Mycosis Fungoides Cooperative Group has been following patients with cutaneous T-cell lymphoma, including mycosis fungoides and the Sézary syndrome variant. Previous analyses identified the extent of skin involvement and the number of sites of clinically enlarged lymph nodes as important prognos...

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Bibliographic Details
Published inAnnals of internal medicine Vol. 100; no. 2; p. 187
Main Authors Lamberg, S I, Green, S B, Byar, D P, Block, J B, Clendenning, W E, Douglas, M C, Epstein, Jr, E H, Fuks, Z Y, Golitz, L E, Lorincz, A L
Format Journal Article
LanguageEnglish
Published United States 01.02.1984
Subjects
Humans
Lymph Nodes - pathology
Lymphoma - mortality
Lymphoma - pathology
Mycosis Fungoides - pathology
Neoplasm Staging
Prognosis
Sezary Syndrome - pathology
Skin Neoplasms - mortality
Skin Neoplasms - pathology
T-Lymphocytes
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Summary:The Mycosis Fungoides Cooperative Group has been following patients with cutaneous T-cell lymphoma, including mycosis fungoides and the Sézary syndrome variant. Previous analyses identified the extent of skin involvement and the number of sites of clinically enlarged lymph nodes as important prognostic variables. These two variables were used to classify 340 patients into four clinical stages. Repeat analysis based on additional followup data shows the usefulness of this clinical staging system for identifying patients with differing survival experience. An alternative grouping suggested by fitting a survival model to the data also has been studied. Staging systems based only on skin involvement and lymph nodes are recommended for general use because the information needed is readily available, requiring only physical examination.
ISSN:0003-4819
DOI:10.7326/0003-4819-100-2-187