Effect of the Glutamine‐Analogue “Azaserine” on Embryonic Development of the Horseshoe Crab

Embryos of the horseshoe crab were treated with the glutamine‐analogue “azaserine”. This compound induced malformed embryos at the stage of enlargement of the germ disc. The embryonic areas of these monsters were separated into two pieces. This is the first report of monsters induced with azaserine....

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Bibliographic Details
Published inDevelopment, growth & differentiation Vol. 24; no. 3; pp. 295 - 303
Main Author ITOW, TOMIO
Format Journal Article
LanguageEnglish
Published Oxford, UK Blackwell Publishing Ltd 1982
Subjects
Marine
Tachypleus tridentatus
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Summary:Embryos of the horseshoe crab were treated with the glutamine‐analogue “azaserine”. This compound induced malformed embryos at the stage of enlargement of the germ disc. The embryonic areas of these monsters were separated into two pieces. This is the first report of monsters induced with azaserine. The effect of azaserine was counteracted by glutamine. Azaserine repressed cell growth of the embryos, and prevented development of their germ disc. During active morphogenic movement, the embryonic area of treated embryos was separated in the central region of elongation of the embryonic area.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0012-1592
1440-169X
DOI:10.1111/j.1440-169X.1982.00295.x