Topical application of a commercially available formulation of vitamin C stabilized by vitamin E and ferulic acid reduces tissue viability and protein synthesis in ex vivo human normal skin

• Published in: Journal of cosmetic dermatology Vol. 19; no. 11; pp. 2965 - 2973
• Main Authors: Romana‐Souza, Bruna, Silva‐Xavier, Welker, Monte‐Alto‐Costa, Andréa
• Format: Journal Article
• Language: English
• Published: England 01.11.2020
• Subjects: Ascorbic Acid - pharmacology; Coumaric Acids - pharmacology; ex vivo model; human skin; Humans; Skin; skin viability; Tissue Survival; vitamin C; vitamin E; Vitamin E - pharmacology; skin viability; ex vivo model; vitamin C; human skin; vitamin E

Background Aqueous formulations of vitamin C stabilized by vitamin E and ferulic acid at low pH effectively protect skin against reactive oxygen species‐induced damage. However, the effects of these formulations on human skin have not clearly been described. The aim of this study was to investigate...