Reaction of 1-chloromethyl-4,5-dichloropyridazin-6-one

Reaction of 1-chloromethyl-4,5-dichloropyridazin-6-one with some nucleophiles such as sodium methoxide, sodium azide, 2-mercaptopyrimidine and phenol gave 2, 3, 4, 7, 8 and 10. 5-Chloro-4-phenoxypyridazin-6-one (10) was also synthesized from 8 through 9.

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Bibliographic Details
Published inJournal of heterocyclic chemistry Vol. 35; no. 6; pp. 1257 - 1261
Main Authors Chung, HA, Kang, YJ, Yoon, YJ
Format Journal Article
LanguageEnglish
Published HOBOKEN Wiley 01.11.1998
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
CHLORIDES
4,5-DICHLORO-1-HYDROXYMETHYLPYRIDAZIN-6-ONE
N-HYDROXYMETHYLSACCHARIN
RETRO-ENE REACTIONS
ALKYL-HALIDES
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Summary:Reaction of 1-chloromethyl-4,5-dichloropyridazin-6-one with some nucleophiles such as sodium methoxide, sodium azide, 2-mercaptopyrimidine and phenol gave 2, 3, 4, 7, 8 and 10. 5-Chloro-4-phenoxypyridazin-6-one (10) was also synthesized from 8 through 9.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.5570350603