Development of Portable Electrical-cell-substrate Impedance Sensing System

We propose a compact electrical-cell-substrate impedance sensing (ECIS) system. The ECIS system measures the amount of microorganisms cultivated in an incubator and monitors it in real time. This is based on the measurement of the AC impedance change of a small goldfilm electrode on a culture well....

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Bibliographic Details
Published inSensors and materials Vol. 31; no. 2; p. 253
Main Authors Park, Chan-Young, Min, Jae-Hong, Kim, Yu-Seop, Song, Hye-Jeong, Kim, Jong-Dae
Format Journal Article
LanguageEnglish
Published Tokyo MYU Scientific Publishing Division 01.01.2019
Subjects
Batteries
Data buses
Electric wire
Energy conservation
Impedance measurement
Lock in amplifiers
Microorganisms
Personal computers
Sensors
Substrates
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Summary:We propose a compact electrical-cell-substrate impedance sensing (ECIS) system. The ECIS system measures the amount of microorganisms cultivated in an incubator and monitors it in real time. This is based on the measurement of the AC impedance change of a small goldfilm electrode on a culture well. In the existing system, except for sensors for impedance measurement, we needed external equipment such as a lock-in amplifier and a personal computer. Also, the sensors inside the incubator and the systems on the outside were connected by a wire. These make the laboratory complex and the system difficult to install. In this study, we implemented a small integrated ECIS system with a recent USB oscilloscope, a battery, and Wi-Fi technology to solve the above problems. System integration allows the entire system to be placed in an incubator, eliminating the need for external systems. Also, it is easy to carry and install it because of its simple structure. A Wi-Fi antenna was used to provide network connectivity inside the incubator to provide a web interface for status monitoring. The system is in the power-saving mode except when measuring to save on battery power. Experimental results on the relationship between measurement interval and battery capacity are given.
ISSN:0914-4935
DOI:10.18494/SAM.2019.2091