An immunological enhancement phenomenon in experimental brucella infection of the chicks

The passive transfer of chicken anti-brucella immune globulins promote the survival of Brucella abortus in the spleen of chickens infected with this bacteria. This enhancing effect was reduced significantly when the immune globulins were absorbed with heat-killed brucella cells to remove all the ant...

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Bibliographic Details
Published inInternational archives of allergy and applied immunology Vol. 53; no. 2; p. 190
Main Authors Forget, A, Borduas, A G
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.1977
Subjects
Animals
Antibodies, Bacterial - administration & dosage
Brucella abortus - growth & development
Brucella abortus - immunology
Brucellosis - immunology
Immunization, Passive
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Summary:The passive transfer of chicken anti-brucella immune globulins promote the survival of Brucella abortus in the spleen of chickens infected with this bacteria. This enhancing effect was reduced significantly when the immune globulins were absorbed with heat-killed brucella cells to remove all the anti-brucella agglutinins and immune adherence antibodies. Therefore, it is most probable that the enhancing effect is related to the presence of brucella antibodies.
ISSN:0020-5915
DOI:10.1159/000231751