Endoscopic mucosal resection of early esophageal squamous cell cancer using the Duette mucosectomy kit

• Published in: Endoscopy Vol. 38; no. 10; p. 1029
• Main Authors: Seewald, S, Ang, T L, Omar, S, Groth, S, Dy, F, Zhong, Y, Seitz, U, Thonke, F, Yekebas, E, Izbicki, J, Soehendra, N
• Format: Journal Article
• Language: English
• Published: Germany 01.10.2006
• Subjects: Aged; Aged, 80 and over; Carcinoma, Squamous Cell - pathology; Carcinoma, Squamous Cell - surgery; Endoscopy, Gastrointestinal - methods; Esophageal Neoplasms - pathology; Esophageal Neoplasms - surgery; Female; Follow-Up Studies; Humans; Intestinal Mucosa - pathology; Intestinal Mucosa - surgery; Male; Middle Aged; Neoplasm Staging; Retrospective Studies; Time Factors; Treatment Outcome
• ISSN: 0013-726X
• DOI: 10.1055/s-2006-944527

Endoscopic mucosal resection (EMR) is a less invasive alternative treatment strategy to surgery for intramucosal esophageal squamous cell carcinoma (SCC). This study described our initial experience with the newly introduced Duette Multiband Mucosectomy Kit (Cook Ireland Ltd, Limerick, Ireland) for the treatment of extensive early esophageal SCC. Five patients with extensive early esophageal SCC, covering at least half of the circumference of the esophageal wall and measuring a mean of 2.8 cm longitudinally, underwent EMR after EUS staging. EMR was successfully completed in one session in five patients. Post-EMR stricture occurred in four patients but was successfully treated with bougienage. One patient did not return for follow-up after bougienage and died from ischemic heart disease 3 months later. For the remaining four patients, there was no recurrence over a mean follow up of 14.7 months. This new device obviates the need for repeated insertion of the endoscope during the process of ligation and resection and thus facilitates EMR of extensive SCC.