Prolapse of the mitral valve: clinical, hemodynamic, angiographic and echocardiographic correlations

Among 1,519 patients undergoing diagnostic cardiac catheterization over a 2-year period, angiographically unequivocal mitral valve prolapse was identified in 79 cases (5.2%). Mitral valve prolapse was clinically unsuspected in 30 of these 79 patients. Echocardiographic studies were available in 44 c...

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Published inCardiology Vol. 63; no. 6; p. 321
Main Authors Iskandrian, A S, Kotler, M N, Kimbiris, D, Levites, R, Bemis, C E, Mintz, G, Forman, H
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.1978
Subjects
Adolescent
Adult
Aged
Angiocardiography
Cardiac Catheterization
Coronary Disease - complications
Echocardiography
Electrocardiography
Female
Heart Septal Defects, Atrial - complications
Heart Valve Diseases - complications
Hemodynamics
Humans
Male
Middle Aged
Mitral Valve Prolapse - diagnosis
Mitral Valve Prolapse - diagnostic imaging
Mitral Valve Prolapse - physiopathology
Phonocardiography
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Summary:Among 1,519 patients undergoing diagnostic cardiac catheterization over a 2-year period, angiographically unequivocal mitral valve prolapse was identified in 79 cases (5.2%). Mitral valve prolapse was clinically unsuspected in 30 of these 79 patients. Echocardiographic studies were available in 44 cases, but only 55% of the patients with prolapse of the mitral valve documented by angiography had positive echocardiographic findings. One third of the patients had associated coronary artery disease, aortic valve disease or atrial septal defects. 14 patients (18%) had moderate or severe mitral regurgitation. There was a wide spectrum of hemodynamic and ventriculographic abnormalities that could not entirely be explained by the degree of prolapse, by the severity of mitral regurgitation or by the presence of associated diseases.
ISSN:0008-6312
1421-9751
DOI:10.1159/000169913