Modified antibody response in rabbits treated with diphenylhydantoin

Rabbits immunized subcutaneously with a mixture of normal human serum, Freund's complete adjuvant and a soluble diphenylhydantoin preparation, produced antibodies that differed qualitatively and quantitatively from the controls, as revealed by immunoelectrophoresis and passive haemagglutination...

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Bibliographic Details
Published inInternational archives of allergy and applied immunology Vol. 53; no. 2; p. 186
Main Author Fossan, G O
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.1977
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Summary:Rabbits immunized subcutaneously with a mixture of normal human serum, Freund's complete adjuvant and a soluble diphenylhydantoin preparation, produced antibodies that differed qualitatively and quantitatively from the controls, as revealed by immunoelectrophoresis and passive haemagglutination. Antibodies in human IgG were greatly increased, whereas antibodies to human albumin were not influenced, and antibodies to some alpha- and beta-globulins were reduced.
ISSN:0020-5915
DOI:10.1159/000231750