Modified antibody response in rabbits treated with diphenylhydantoin

Rabbits immunized subcutaneously with a mixture of normal human serum, Freund's complete adjuvant and a soluble diphenylhydantoin preparation, produced antibodies that differed qualitatively and quantitatively from the controls, as revealed by immunoelectrophoresis and passive haemagglutination...

Full description

Saved in:
Bibliographic Details
Published inInternational archives of allergy and applied immunology Vol. 53; no. 2; p. 186
Main Author Fossan, G O
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.1977
Subjects
Animals
Antibodies, Anti-Idiotypic - biosynthesis
Antibody Formation - drug effects
Immunoglobulin G
Phenytoin - pharmacology
Rabbits
Serum Albumin - immunology
Online AccessGet more information

Cover

More Information
Summary:Rabbits immunized subcutaneously with a mixture of normal human serum, Freund's complete adjuvant and a soluble diphenylhydantoin preparation, produced antibodies that differed qualitatively and quantitatively from the controls, as revealed by immunoelectrophoresis and passive haemagglutination. Antibodies in human IgG were greatly increased, whereas antibodies to human albumin were not influenced, and antibodies to some alpha- and beta-globulins were reduced.
ISSN:0020-5915
DOI:10.1159/000231750