Renal complications associated with human parvovirus B19 infection in early childhood

A previously healthy two-year-old girl presented with proteinuria and macroscopic haematuria. Laboratory findings included haemolytic anaemia with thrombocytopenia. Interestingly, continuing reticulocytopenia was noted. Therefore an acute parvovirus B19 infection was suspected, which could be confir...

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Bibliographic Details
Published inKlinische Pädiatrie Vol. 219; no. 2; p. 74
Main Authors Härtel, C, Herz, A, Vieth, S, Lensing, C, Schultz, C
Format Journal Article
LanguageEnglish
Published Germany 01.03.2007
Subjects
Child, Preschool
Diagnosis, Differential
Diuretics - administration & dosage
Female
Fluid Therapy
Furosemide - administration & dosage
Glomerulonephritis - diagnosis
Glomerulonephritis - therapy
Glomerulonephritis - virology
Hematuria - virology
Hemolytic-Uremic Syndrome - diagnosis
Hemolytic-Uremic Syndrome - therapy
Hemolytic-Uremic Syndrome - virology
Humans
Parvoviridae Infections - diagnosis
Parvoviridae Infections - therapy
Parvoviridae Infections - virology
Parvovirus B19, Human - genetics
Parvovirus B19, Human - pathogenicity
Polymerase Chain Reaction
Proteinuria - virology
Virulence
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Summary:A previously healthy two-year-old girl presented with proteinuria and macroscopic haematuria. Laboratory findings included haemolytic anaemia with thrombocytopenia. Interestingly, continuing reticulocytopenia was noted. Therefore an acute parvovirus B19 infection was suspected, which could be confirmed by serological and molecularbiological evidence. This case report underlines renal complications of parvovirus B19 infection in early childhood including haemolytic-uraemic syndrome (HUS)-like episodes, and potential pathogenetic mechanisms are discussed.
ISSN:0300-8630
DOI:10.1055/s-2007-970071