Stress response in Drosophila melanogaster strain inactive with decreased tyramine and octopamine contents

• Published in: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology Vol. 172; no. 7; pp. 643 - 650
• Main Authors: Chentsova, N A, Gruntenko, N E, Bogomolova, E V, Adonyeva, N V, Karpova, E K, Rauschenbach, I Yu
• Format: Journal Article
• Language: English
• Published: Germany 01.10.2002
• Subjects: Animals; Dopamine - metabolism; Drosophila melanogaster - physiology; Fertility; Hot Temperature; Juvenile Hormones - metabolism; Octopamine - metabolism; Species Specificity; Stress, Physiological - physiopathology; Survival Analysis; Tyramine - metabolism; Tyrosine Decarboxylase - metabolism
• ISSN: 0174-1578; 1432-136X
• DOI: 10.1007/s00360-002-0293-9

Juvenile hormone hydrolysis, tyrosine decarboxylase activity, dopamine content and fitness (viability and fertility) were studied under normal and stress conditions in the adults of Drosophila melanogaster inactive strain carrying a mutation that decreases tyrosine decarboxylase activity and results in the lower contents of tyramine and octopamine. A sexual dimorphism of tyrosine decarboxylase activity, dopamine level and survival under heat stress in inactive flies was found. inactive adults showed higher dopamine levels and lower survival levels under heat stress as compared to wild type (Canton S) adults. Juvenile hormone degradation is decreased in young and increased in mature inactive females as compared to wild type. Fertility of the inactive strain did not differ from that of wild type strain under normal conditions, but after heat exposure the dynamics of its restoration was different. inactive females were found to develop the stress reaction, with juvenile hormone degradation, tyrosine decarboxylase activity, dopamine content and fertility levels used as the reaction indicators.