Squamous cell carcinoma arising in a Zenker diverticulum

Abstract Squamous cell carcinoma (SCC) arising in a Zenker diverticulum (ZD) is an extremely rare entity. Approximately 50 cases have been reported worldwide. We report a case of a 74-year-old man who presented to our institution with chronic regurgitation, dysphagia and halitosis. The patient was i...

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Published inJournal of surgical case reports Vol. 2022; no. 9
Main Authors Polit, Francesca, Bahmad, Hisham F, Wahi, Jessica, Deb, Arunima, Newsome, Kevin, Howard, Lydia, Poppiti, Robert, Ben-David, Kfir, Alghamdi, Sarah
Format Journal Article
LanguageEnglish
Published Oxford University Press 01.09.2022
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Summary:Abstract Squamous cell carcinoma (SCC) arising in a Zenker diverticulum (ZD) is an extremely rare entity. Approximately 50 cases have been reported worldwide. We report a case of a 74-year-old man who presented to our institution with chronic regurgitation, dysphagia and halitosis. The patient was initially seen in 2015 at which point he reported a 10-year history of these symptoms and was diagnosed with ZD. A barium swallow was done revealing a large posterior esophageal diverticulum with significant residual contrast within the diverticulum lumen. Given these findings, he was taken for open surgical excision where a SCC was identified. Although it is extremely rare for a SCC to occur in a ZD, patients with ZD must undergo regular surveillance endoscopy of the esophagus and the diverticulum itself to identify any suspicious mass or lesion arising in within.
Bibliography:F. Polit and H.F. Bahmad contributed equally to this work as co-first authors.
ISSN:2042-8812
2042-8812
DOI:10.1093/jscr/rjac458