Multiplication of Babesia gibsoni in In vitro Culture and Its Relation to Hemolysis of Infected Erythrocytes

Babesia gibsoni is a well-known blood parasite in the dog and causes hemolytic anemia in infected dogs. The life cycle of the parasite, and the pathogenesis of the anemia, however, have not yet been fully elucidated. To clarify these problems in vitro culture of the parasite seems to be needed, but...

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Bibliographic Details
Published inJournal of Veterinary Medical Science Vol. 53; no. 4; pp. 759 - 760
Main Authors MURASE, Toshiyuki, HASHIMOTO, Takeshi, UEDA, Takeo, MAEDE, Yoshimitsu
Format Journal Article
LanguageEnglish
Published Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 1991
Subjects
Animals
Babesia - growth & development
Babesia gibsoni
Cells, Cultured
culture
Dogs
Erythrocytes - parasitology
Hemolysis
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Summary:Babesia gibsoni is a well-known blood parasite in the dog and causes hemolytic anemia in infected dogs. The life cycle of the parasite, and the pathogenesis of the anemia, however, have not yet been fully elucidated. To clarify these problems in vitro culture of the parasite seems to be needed, but it has not been successfully achieved until now. In the present study, B. gibsoni was successfully cultured in a settled layer of canine erythrocytes. Using this method for cultivation, we investigated the relationship between morphological changes in the intraerythrocytic parasites and hemolysis of erythrocytes during the cultivation.
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ISSN:0916-7250
1347-7439
DOI:10.1292/jvms.53.759