Chronic ischial tuberosity avulsion nonunion fracture treated with a platelet-rich plasma injection as a bone graft

• Published in: Regenerative medicine Vol. 14; no. 5; pp. 353 - 358
• Main Authors: Stafford, Cleo D, Colberg, Ricardo E, Nourse, Alexander L
• Format: Journal Article
• Language: English
• Published: England Future Medicine Ltd 01.05.2019
• Subjects: Adolescent; bone graft; Bone Transplantation; Defects; Fractures; Fractures, Bone - diagnostic imaging; Fractures, Bone - pathology; Fractures, Bone - therapy; Humans; Injuries; ischial apophyseal injury; ischial tuberosity avulsion; Ischium - injuries; Male; Pain; Plasma; Platelet-Rich Plasma; platelet-rich plasma (PRP); Rehabilitation; Skin & tissue grafts; Systematic review; Tomography; Ultrasonic imaging; ultrasound guided injection; United States > US; ischial tuberosity avulsion; bone graft; ultrasound guided injection; ischial apophyseal injury; platelet-rich plasma (PRP)
• ISSN: 1746-0751; 1746-076X
• DOI: 10.2217/rme-2018-0071

We present a case of an 18-year-old with a 2-year history of buttock pain who failed extensive treatment for a perceived hamstring strain. Upon evaluation, he was diagnosed with an ischial tuberosity nonunion avulsion fracture. The patient underwent bone grafting via an ultrasound guided leukocyte rich platelet-rich plasma injection followed by the use of a bone stimulator to enhance the bone healing. At 3 months, he was asymptomatic and had radiographic evidence of excellent bone healing. He remained asymptomatic at 1 year and had resumed full activities. This case report is the first in the literature to describe the treatment of a chronic ischial tuberosity nonunion avulsion fracture with the use of platelet-rich plasma as a bone graft.