Synthesis and Antibacterial Evaluation of Some Novel 2-Arylamino-4-phenyl-thiazolyl Derivatives

A series of 2-aminothiazoles derivatives have been synthesized and tested for in vitro antibacterial activity on different microorganisms. Syntheses have been carried out following simple methodology in excellent isolated yields. The structure and purity of the original compounds were confirmed by I...

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Bibliographic Details
Published inBulletin of the Korean Chemical Society Vol. 31; no. 4; pp. 793 - 797
Main Authors Parmar, Kokila A., Suthar, Bharat G., Parajapati, Sarju
Format Journal Article
LanguageEnglish
Published 대한화학회 20.04.2010
Subjects
화학
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Summary:A series of 2-aminothiazoles derivatives have been synthesized and tested for in vitro antibacterial activity on different microorganisms. Syntheses have been carried out following simple methodology in excellent isolated yields. The structure and purity of the original compounds were confirmed by IR, NMR, Mass spectroscopy, and elemental analysis. All compounds were tested for antibacterial activity against S. aureus, S. pyogenes, E. coli, P. aeruginosa, S. typhi and V. parahaemolyticus. These preliminary results indicate that some of compounds are exhibiting good activity. KCI Citation Count: 7
Bibliography:G704-000067.2010.31.4.067
ISSN:0253-2964
1229-5949
DOI:10.5012/bkcs.2010.31.04.793