Allergenic activity of fractions of cocksfoot (Dactylis glomerata) pollen. Definition of active components by skin testing, and inhibition RAST

With the combined use of skin tests, RAST and isoelectric focusing, a potency profile of a cocksfoot ((Dactylis glomerata) pollen extract was prepared. It was found that two fractions with pI 4.5 and 6.0 were the most allergenic, had the highest protein concentration and were also the most easily ex...

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Bibliographic Details
Published inClinical allergy Vol. 11; no. 3; pp. 281 - 286
Main Authors Topping, M D, Brostoff, J, Brighton, W D
Format Journal Article
LanguageEnglish
Published England 01.05.1981
Subjects
Allergens
Chemical Fractionation
Humans
Isoelectric Focusing
Pollen
Radioallergosorbent Test
Skin Tests
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Summary:With the combined use of skin tests, RAST and isoelectric focusing, a potency profile of a cocksfoot ((Dactylis glomerata) pollen extract was prepared. It was found that two fractions with pI 4.5 and 6.0 were the most allergenic, had the highest protein concentration and were also the most easily extracted. The importance of converting mean weal sizes into potency units when comparing the allergenicity of pollen fractions is emphasized.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0009-9090
DOI:10.1111/j.1365-2222.1981.tb01595.x