Application of copper(I)-catalysed azide/alkyne cycloaddition (CuAAC) ‘click chemistry’ in carbohydrate drug and neoglycopolymer synthesis

• Published in: Tetrahedron Vol. 66; no. 49; pp. 9475 - 9492
• Main Authors: Aragão-Leoneti, Valquiria, Campo, Vanessa L., Gomes, Adriane S., Field, Robert A., Carvalho, Ivone
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 04.12.2010; Elsevier
• Subjects: Carbohydrate bioactive compounds; Carbohydrates with 4, 5, 6, ... C atoms, dissacharides and oligosaccharides; Carbohydrates. Nucleosides and nucleotides; Chemistry; Click chemistry; Copper(I)-catalysed azide/alkyne cycloaddition; Exact sciences and technology; Huisgen 1,3-dipolar cycloaddition; Neoglycopolymers; Organic chemistry; Preparations and properties; XUFXOAAUWZOOIT-YTXROHJBSA-N; BPJHSADGRVWJFX-YNMRTIPJSA-N; Copper(I)-catalysed azide/alkyne cycloaddition; FKUZKLYUXNAMLV-NMDCEIODSA-N; Carbohydrate bioactive compounds; FMFBZUNGGGBDFQ-WIFHLUGASA-L; YNMYIBWSLUTLDL-SKIYYFIFSA-N; LZMIOMPWNQQNME-WIWXMOHPSA-N; GBTPJZFWBCZBIS-MWRNNASUSA-N; GIUGVKNPDPWZNK-DPFTZIENSA-N; Neoglycopolymers; OBLCPCWIQTWCAC-WJNAHZSFSA-N; Huisgen 1,3-dipolar cycloaddition; INJFDFJARXLTAG-WUERDQBYSA-N; Click chemistry; FFWULPKYVDFIGW-BTFPBAQTSA-N; Drug; 1,3-Dipolar cycloaddition; Catalytic reaction; Acetylenic compound; Organic azide; Oside; Biological activity; Huisgen cycloaddition; Azides; Copper(I)-catalysed azide/alkyne; cycloaddition; Copper I; Chemical synthesis; Alkyne
• ISSN: 0040-4020; 1464-5416
• DOI: 10.1016/j.tet.2010.10.001

An overview of the potential application of copper(I)-catalysed azide/alkyne cycloaddition (CuAAC) ‘click chemistry’ in the synthesis of bioactive carbohydrates and neoglycopolymers is described. [Display omitted]