The relation of anthropometric measurements and insulin resistance in patients with polycystic kidney disease

To examine the frequency of insulin resistance (IR) and its relation with anthropometric measurements in patients with autosomal dominant polycystic kidney disease (ADPKD). Nonobese 82 patients with ADPKD and 58 age matched healthy controls were enrolled into the study. None of participants were dia...

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Bibliographic Details
Published inJournal of translational internal medicine Vol. 4; no. 3; pp. 127 - 134
Main Authors Esen, Bennur, Gokmen, Emel Sağlam, Kaya, Mahmut, Ozkan, Burak, Atay, Ahmet Engin
Format Journal Article
LanguageEnglish
Published Poland De Gruyter 01.09.2016
Subjects
anthropometric measurements
diabetes mellitus
insulin resistance
obesity
Original
polycystic kidney disease
anthropometric measurements
diabetes mellitus
polycystic kidney disease
insulin resistance
obesity
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Summary:To examine the frequency of insulin resistance (IR) and its relation with anthropometric measurements in patients with autosomal dominant polycystic kidney disease (ADPKD). Nonobese 82 patients with ADPKD and 58 age matched healthy controls were enrolled into the study. None of participants were diabetic or receiving renal replacement therapies (RRT). IR was determined by homeostasis model assessment of insulin resistance (HOMA-IR) formula. Tanita body composition analyzer was used for anthropometric measurements. Creatinine clearance of participant were assessed by the modification of diet in renal diseases (MDRD). Patients with ADPKD had significantly higher level of urea and creatinine, microalbuminuria, and lower level of MDRD. Body fat distribution and HOMA-IR in both the groups were similar. Systolic and diastolic blood pressure of patients were higher than those of controls. We failed to determine a higher frequency of IR among patients with ADPKD.
ISSN:2450-131X
2224-4018
2224-4018
DOI:10.1515/jtim-2016-0029