N-Alkoxy-N-chloroureas in the synthesis of 3,4-dihydro-1H-2,1-benzoxazine-1-carboxamide and 1-alkoxy-1,3-dihydrobenzimidazol-2-ones
The cyclization of N -chloro- N -(2-phenylethoxy)urea in the presence of silver trifluoroacetate leads to the formation of 3,4-dihydro-1 H -2,1-benzoxazine-1-carboxamide, while N -alkoxy- N '-aryl- N -chloro-ureas in the presence of sodium acetate form 1-alkoxy-1,3-dihydrobenzimidazol-2-ones. T...
Saved in:
Published in | Chemistry of heterocyclic compounds (New York, N.Y. 1965) Vol. 49; no. 8; pp. 1195 - 1206 |
---|---|
Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Boston
Springer US
01.11.2013
Springer Nature Springer |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The cyclization of
N
-chloro-
N
-(2-phenylethoxy)urea in the presence of silver trifluoroacetate leads to the formation of 3,4-dihydro-1
H
-2,1-benzoxazine-1-carboxamide, while
N
-alkoxy-
N
'-aryl-
N
-chloro-ureas in the presence of sodium acetate form 1-alkoxy-1,3-dihydrobenzimidazol-2-ones. The structures of 3,4-dihydro-1
H
-2,1-benzoxazine-1-carboxamide and 1-methoxy-6-nitro-1,3-dihydrobenzimidazol-2-one were examined by X-ray structural analysis. |
---|---|
ISSN: | 0009-3122 1573-8353 |
DOI: | 10.1007/s10593-013-1363-5 |