Stereoselection in designed three-helix bundle metalloproteins
The stereochemical consequences of the metal‐ion assisted self‐assembly of parallel three‐helix peptide bundles are investigated. Chiral induction in the self‐assembly of systems containing extensive protein secondary structure is compared with the racemic synthesis of short metallopeptides. Isolati...
Saved in:
Published in | Chirality (New York, N.Y.) Vol. 10; no. 1-2; pp. 35 - 40 |
---|---|
Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
New York
John Wiley & Sons, Inc
1998
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The stereochemical consequences of the metal‐ion assisted self‐assembly of parallel three‐helix peptide bundles are investigated. Chiral induction in the self‐assembly of systems containing extensive protein secondary structure is compared with the racemic synthesis of short metallopeptides. Isolation and characterization of the individual stereoisomers of an exchange‐inert metalloprotein provide structural insights into analogous exchange‐labile systems. Chirality 10:35–40, 1998. © 1998 Wiley‐Liss,Inc. |
---|---|
Bibliography: | ark:/67375/WNG-PBHX5VST-H ArticleID:CHIR7 istex:6994DF0B821B97197FEB436B7F6D6EAF98FBF32D ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0899-0042 1520-636X |
DOI: | 10.1002/chir.7 |