Synthesis and Biological Activity of 4,5-Dihydro-1,2,4-triazole-5-thione Schiff Base

• Published in: Chinese journal of chemistry Vol. 27; no. 7; pp. 1397 - 1400
• Main Authors: SUN, Xiaohong, BAI, Yan, LIU, Yuanfa, CHEN, Bang, JIA, Yingqi, ZENG, Zhenfang
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 01.07.2009; WILEY‐VCH Verlag; Wiley
• Subjects: biological activity; Chemistry; Chemistry, Multidisciplinary; Physical Sciences; Schiff base; Science & Technology; synthesis; triazole; Schiff base; synthesis; biological activity; triazole

The 4,5‐dihydro‐1,2,4‐triazole Schiff base derivatives were synthesized with 4‐amino‐4,5‐dihydro‐3‐(phenoxy‐ methyl)‐1H‐1,2,4‐triazole‐5‐thione and substituted benzaldehydes. The chemical structures of the compounds have been confirmed by 1H NMR, IR spectra and elemental analysis. Their biological a...