Measurement of human chorionic gonadotrophin (hCG): indications and techniques for the clinical laboratory

The structure of human chorionic gonadotrophin (hCG) is so similar to that of luteinizing hormone (LH) that a variety of assay techniques have been devised to differentiate between these two hormones. The principal indications for measurement of hCG using these methods have not changed greatly over...

Full description

Saved in:
Bibliographic Details
Published inAnnals of clinical biochemistry Vol. 27 ( Pt 3); p. 183
Main Authors Norman, R J, Buck, R H, De Medeiros, S F
Format Journal Article
LanguageEnglish
Published England 01.05.1990
Subjects
Amino Acid Sequence
Chorionic Gonadotropin - analysis
Chorionic Gonadotropin - physiology
Chorionic Gonadotropin - secretion
Humans
Immunologic Techniques
Molecular Sequence Data
Protein Conformation
Sensitivity and Specificity
Online AccessGet more information

Cover

More Information
Summary:The structure of human chorionic gonadotrophin (hCG) is so similar to that of luteinizing hormone (LH) that a variety of assay techniques have been devised to differentiate between these two hormones. The principal indications for measurement of hCG using these methods have not changed greatly over the past decade but the improvements in the sensitivity, specificity and the development of assays for free subunits and metabolic fragments have expanded the use of hCG assays. The review discusses the use of hCG measurement in a routine clinical immunoassay laboratory and emphasizes different requirements for clinical situations.
ISSN:0004-5632
DOI:10.1177/000456329002700302