Dental autotransplantation: a viable solution for preserving oral health and function

• Published in: Evidence-based dentistry Vol. 25; no. 2; pp. 77 - 78
• Main Authors: Mourão, Carlos Fernando, Resende, Rodrigo
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.06.2024; Nature Publishing Group
• Subjects: 692/700/3032/3098; 692/700/3032/3099/3111; Ankylosis; Comment; Dentistry; Humans; Medical prognosis; Medicine; Meta-analysis; Oral Health; Quality control; Reviews; Root resorption; Success; Survival; Systematic Reviews as Topic; Tooth - transplantation; Transplantation, Autologous - methods
• ISSN: 1462-0049; 1476-5446; 1476-5446
• DOI: 10.1038/s41432-024-01002-w

Design An umbrella review of systematic reviews and meta-analyses on dental autotransplantation (DAT). Aim To provide a comprehensive overview of the current state of knowledge on prognostic factors, outcomes, and complications of DAT by synthesizing the evidence. Methods A comprehensive search of six databases was conducted for systematic reviews and meta-analyses published up to June 30, 2022. Two authors independently performed study selection, data extraction, and quality assessment using the AMSTAR 2 tool. Raw data from primary studies were analyzed using a random effects meta-analysis, and meta-regression was performed to investigate the effect of open and closed apices on the outcomes. Results Ten systematic reviews, of which nine included meta-analyses, were examined. The overall success rate of the studies was 89.4%, and the survival rate was 96.1%. The main complications were ankylosis (4.6%) and root resorption (7.4%). The analysis showed that a closed apex increased the proportion of ankylosis, resorption, and reduced survival but had no effect on success. The quality of the systematic reviews included varied, with 20% scoring moderate, 60% scoring low, and 20% scoring critically low on the AMSTAR 2 scale. Conclusions Dental implant therapy is a reliable solution for replacing lost or damaged teeth, with high success and survival rates. However, it is a procedure that requires precision and attention to detail, along with careful selection of suitable candidates, comprehensive planning, and consideration of factors that may impact outcomes. To improve results and reduce potential complications, it is essential to establish standard clinical guidelines and conduct further extensive research.