Sensorineural Deafness Following Tacrolimus Use

Early trials of tacrolimus in renal transplant recipients have not revealed hearing loss as an adverse effect. Here, we present a case report and a review of the literature of deafness after tacrolimus use. The review of the literature and our experience suggested that the possible reason for hearin...

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Bibliographic Details
Published inExperimental and clinical transplantation Vol. 18; no. 1; pp. 110 - 111
Main Authors Lakshmi, Boju Sangeetha, Vidya, Bhukya, Reddy, Mogili Hari Krishna, Kumar, Anil Cheni Venkata, Ram, Rapur, Kumar, Vishnubotla Siva
Format Journal Article
LanguageEnglish
Published Turkey Başkent Üniversitesi 01.02.2020
Subjects
Tıp
Ankara
Türkiye
Drug effects
Renal transplant
Hearing loss
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Summary:Early trials of tacrolimus in renal transplant recipients have not revealed hearing loss as an adverse effect. Here, we present a case report and a review of the literature of deafness after tacrolimus use. The review of the literature and our experience suggested that the possible reason for hearing loss could be due to an initiation of a sudden spike in the tacrolimus serum level, which was later worsened by its cumulative toxic effect.
ISSN:1304-0855
2146-8427
DOI:10.6002/ect.2017.0114