Rapid detection of fibrinogen and fibrin degradation products using a smart QCM-sensor

We have developed a rapid immunosensor for fibrinogen and fibrin degradation products (FDP) that combines a quartz crystal microbalance (QCM) with the agglutination reaction of anti-FDP antibody immunized latex beads. We measured FDP concentration successfully in human serum within 10min with a smar...

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Bibliographic Details
Published inSensors and actuators. B, Chemical Vol. 101; no. 1-2; pp. 150 - 154
Main Authors Aizawa, Hidenobu, Kurosawa, Shigeru, Tozuka, Mitsuhiro, Park, Jong-Won, Kobayashi, Koichi
Format Journal Article
LanguageEnglish
Published Elsevier B.V 15.06.2004
Subjects
Fibrinogen and fibrin degradation products (FDP)
Immunized latex
Immunosensor
Quartz crystal microbalance (QCM)
Smart QCM-sensor
Immunized latex
Quartz crystal microbalance (QCM)
Fibrinogen and fibrin degradation products (FDP)
Smart QCM-sensor
Immunosensor
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Summary:We have developed a rapid immunosensor for fibrinogen and fibrin degradation products (FDP) that combines a quartz crystal microbalance (QCM) with the agglutination reaction of anti-FDP antibody immunized latex beads. We measured FDP concentration successfully in human serum within 10min with a smart QCM-sensor. The detection range of the smart QCM-sensor is covered with screening concentration of FDP in serum (less than 10μgml−1 of FDP).
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0925-4005
1873-3077
DOI:10.1016/j.snb.2004.02.057