Pulmonary histiocytosis X with mediastinal lymph node involvement

In this report, we describe a patient with the classic histology of pulmonary histiocytosis X, who had bilateral reticulonodular densities and mediastinal lymph node involvement. The diagnosis was confirmed by the use of electron microscopy and immunohistochemical markers (PS100, HLA-DR, and CD1), w...

Full description

Saved in:
Bibliographic Details
Published inThe American review of respiratory disease Vol. 142; no. 5; p. 1216
Main Authors Brambilla, E, Fontaine, E, Pison, C M, Coulomb, M, Paramelle, B, Brambilla, C
Format Journal Article
LanguageEnglish
Published United States 01.11.1990
Subjects
Adult
Histiocytosis, Langerhans-Cell - complications
Histiocytosis, Langerhans-Cell - diagnostic imaging
Histiocytosis, Langerhans-Cell - pathology
Humans
Lung - ultrastructure
Lung Diseases - complications
Lung Diseases - diagnostic imaging
Lung Diseases - pathology
Lymph Nodes - pathology
Lymphatic Diseases - complications
Lymphatic Diseases - pathology
Male
Mediastinal Diseases - complications
Mediastinal Diseases - pathology
Radiography
Online AccessGet more information

Cover

More Information
Summary:In this report, we describe a patient with the classic histology of pulmonary histiocytosis X, who had bilateral reticulonodular densities and mediastinal lymph node involvement. The diagnosis was confirmed by the use of electron microscopy and immunohistochemical markers (PS100, HLA-DR, and CD1), which allowed us to recognize the lymph node infiltration of X histiocytes. An association of mediastinal lymph node enlargement with pulmonary histiocytosis X has been reported but it has never been histologically documented.
ISSN:0003-0805
DOI:10.1164/ajrccm/142.5.1216