Cross-cultural adaptation and psychometric properties of the Brazilian Portuguese version of the Impact of Neurofibromatosis type 1 on Quality of Life (INF1-QoL) questionnaire

• Published in: British journal of dermatology (1951) Vol. 188; no. 5; pp. 689 - 690
• Main Authors: Bicudo, Natália P, Germano, Carla Maria Ramos, de Avó, Lucimar R S, Ferner, Rosalie E, Melo, Débora G
• Format: Journal Article
• Language: English
• Published: England 20.04.2023
• Subjects: Brazil; Cross-Cultural Comparison; Humans; Neurofibromatosis 1 - diagnosis; Psychometrics; Quality of Life; Reproducibility of Results; Surveys and Questionnaires; Translations; Brazil
• ISSN: 0007-0963; 1365-2133
• DOI: 10.1093/bjd/ljad037

This study aimed to adapt the Impact of Neurofibromatosis Type 1 on Quality of Life (INF1-QoL) questionnaire to Brazilian Portuguese and assess its psychometric properties. The INF1-QoL was adapted using a translation-back-translation method, and a pretest was conducted with 101 adults with NF1. Cronbach’s α revealed that the INF1-QoL questionnaire was reliable (0.801). An exploratory factor analysis uncovered two latent factors, which explained 49% of the variance in the results. The factor structure provided adequate composite reliability indices, replicability estimates and goodness-of-fit indices. The INF1-QoL questionnaire was translated, adapted and validated in the Brazilian context. It is a useful patient-reported outcome measure for NF1 healthcare providers in Brazil.