A Novel X-Linked Inhibitor of Apoptosis Deficient Variant Showing Attenuated Epstein-Barr Virus Response

Abstract We report on 2 Asian siblings with X-linked inhibitor of apoptosis deficiency that arose from a novel deletion that presented with Epstein-Barr virus disease and hemophagocytic lymphohistiocytosis. This disease is ascribed to dysfunction in the nucleotide binding and oligomerization domain...

Full description

Saved in:
Bibliographic Details
Published inJournal of the Pediatric Infectious Diseases Society Vol. 10; no. 3; pp. 345 - 348
Main Authors Zhong, Youjia, Huang, Chiung-Hui, Soe, Win Mar, Chan, Koon Wing, Isa, Mas Suhaila, Soh, Jianyi, Yap, Mark, MacAry, Paul Anthony, Lau, Yu-Lung, Chai, Louis Yi Ann, Shek, Lynette Pei-Chi, Lee, Bee Wah
Format Journal Article
LanguageEnglish
Published US Oxford University Press 03.04.2021
Subjects
Online AccessGet full text

Cover

Loading…
More Information
Summary:Abstract We report on 2 Asian siblings with X-linked inhibitor of apoptosis deficiency that arose from a novel deletion that presented with Epstein-Barr virus disease and hemophagocytic lymphohistiocytosis. This disease is ascribed to dysfunction in the nucleotide binding and oligomerization domain receptor pathway, tested using a modified muramyl dipeptide–mediated assay.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2048-7207
2048-7207
DOI:10.1093/jpids/piaa048