Two-birds-one-stone approach to combine protein and mRNA vaccines for COVID-19

COVID-19 vaccines have been successful, but their duration and level of protection could be improved to cover all SARS-CoV-2 variants. A self-assembling enveloped virus-like particle vaccine combining features of mRNA and protein vaccines might provide a way forward.

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Bibliographic Details
Published inNature immunology Vol. 24; no. 7; pp. 1056 - 1057
Main Author Gao, George F.
Format Journal Article
LanguageEnglish
Published New York Nature Publishing Group US 01.07.2023
Nature Publishing Group
Subjects
631/250/590
631/326/596/4130
Antibodies
Biomedical and Life Sciences
Biomedicine
Cell division
COVID-19
COVID-19 vaccines
Efficiency
Immunology
Infections
Infectious Diseases
Influenza
Lipids
mRNA
mRNA vaccines
Nanoparticles
News & Views
news-and-views
Pandemics
Proteins
Severe acute respiratory syndrome coronavirus 2
Vaccines
Virus-like particles
Viruses
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Summary:COVID-19 vaccines have been successful, but their duration and level of protection could be improved to cover all SARS-CoV-2 variants. A self-assembling enveloped virus-like particle vaccine combining features of mRNA and protein vaccines might provide a way forward.
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SourceType-Scholarly Journals-1
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ObjectType-Commentary-3
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ISSN:1529-2908
1529-2916
DOI:10.1038/s41590-023-01539-5