Beyond Smooth Muscle-Other Mesenchymal Neoplasms of the Uterus

Mesenchymal tumors of the uterus comprise a heterogeneous group of neoplasms of varied biologic potential. In addition to being host to several anatomically unique entities, the uterus may contain mesenchymal neoplasms typically found elsewhere in the body. Although smooth muscle neoplasms are commo...

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Bibliographic Details
Published inSurgical pathology clinics Vol. 12; no. 1; p. 107
Main Author Dickson, Brendan C
Format Journal Article
LanguageEnglish
Published United States 01.03.2019
Subjects
Diagnosis, Differential
Female
Humans
Immunohistochemistry
Muscle, Smooth - pathology
Prognosis
Smooth Muscle Tumor - classification
Smooth Muscle Tumor - genetics
Smooth Muscle Tumor - pathology
Uterine Neoplasms - classification
Uterine Neoplasms - genetics
Uterine Neoplasms - pathology
Uterus - pathology
Undifferentiated uterine sarcoma
Uterine tumor resembling ovarian sex cord tumor
PEComa
Endometrial stromal sarcoma
Inflammatory myofibroblastic tumor
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Summary:Mesenchymal tumors of the uterus comprise a heterogeneous group of neoplasms of varied biologic potential. In addition to being host to several anatomically unique entities, the uterus may contain mesenchymal neoplasms typically found elsewhere in the body. Although smooth muscle neoplasms are common, other mesenchymal neoplasms in this location are relatively rare. Many of these neoplasms exhibit morphologic overlap. In addition to a careful histomorphologic review, definitive classification frequently depends on the judicious application of ancillary immunohistochemical and molecular testing. The intent of this review is to offer a basic approach to the classification of primary uterine mesenchymal neoplasms.
ISSN:1875-9157
DOI:10.1016/j.path.2018.10.005