Metal nanoparticles and IR laser applications in medicine for biotissue ablation and welding

We report the possibility of laser welding and ablation of biotissue by using metal and hybrid metal nanoparticles (NPs) and infrared laser irradiation spectrally located far from plasmon resonances. A nanosecond YAG:Nd laser of wavelength 1064 nm has been used for synthesis of metal NPs. The Ag, Au...

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Bibliographic Details
Published inLaser physics Vol. 26; no. 5; pp. 55605 - 55609
Main Authors Lalayan, A A, Israelyan, S S
Format Journal Article
LanguageEnglish
Published IOP Publishing 01.05.2016
Subjects
ablation
biotissue
laser
nanoparticles
welding
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Summary:We report the possibility of laser welding and ablation of biotissue by using metal and hybrid metal nanoparticles (NPs) and infrared laser irradiation spectrally located far from plasmon resonances. A nanosecond YAG:Nd laser of wavelength 1064 nm has been used for synthesis of metal NPs. The Ag, Au, Cu, Ti and Ni, as well as Au-Ag and Au-Cu hybrid metal colloidal NPs were formed in a liquid medium. The diagnostic technique of second harmonic generation (SHG) has been applied to determine the biotissue ablation area after IR laser irradiation. The effectiveness of biotissue ablation was 4-5 times larger in the case of a tissue sample colored with metal NPs than for an uncolored sample. IR laser welding has been demonstrated for deep-located biotissue layers colored by metal NPs.
Bibliography:2015LPL0519
ISSN:1054-660X
1555-6611
DOI:10.1088/1054-660X/26/5/055605