The impact of surgical learning curve on short-term outcomes after bilateral lung transplantation: results from a multidisciplinary surgical team

• Published in: European journal of cardio-thoracic surgery Vol. 64; no. 1
• Main Authors: Chou, Pin-Li, Liu, Kuo-Sheng, Chao, Yin-Kai, Wen, Yu-Wen, Liu, Yun-Hen, Hsieh, Ming-Ju, Chiu, Chien-Hung, Fang, Hsin-Yueh, Cheng, Chia-Hui, Hu, Han-Chung, Chen, Wei-Hsun
• Format: Journal Article
• Language: English
• Published: Germany Oxford University Press 03.07.2023
• Subjects: Learning curve; Lung transplantation; Multidisciplinary team
• ISSN: 1873-734X; 1873-734X
• DOI: 10.1093/ejcts/ezad227

Abstract OBJECTIVES The aim of this study was to examine the impact of surgical learning curve on short-term clinical outcomes of patients after bilateral lung transplantation (LTx) performed by a surgical multidisciplinary team (MDT). METHODS Forty-two patients underwent double LTx from December 2016 to October 2021. All procedures were performed by a surgical MDT in a newly established LTx program. The time required for bronchial, left atrial cuff and pulmonary artery anastomoses was the main end point to assess surgical proficiency. The associations between the surgeon’s experience and procedural duration were examined by linear regression analysis. We employed the simple moving average technique to generate learning curves and evaluated short-term outcomes before and after achieving surgical proficiency. RESULTS Both total operating time and total anastomosis time were inversely associated with the surgeon’s experience. On analysing the learning curve for bronchial, left atrial cuff and pulmonary artery anastomoses using moving averages, the inflection points occurred at 20, 15 and 10 cases, respectively. To assess the learning curve effect, the study cohort was divided into early (cases 1–20) and late (cases 21–42) groups. Short-term outcomes—including intensive care unit stay, in-hospital stay and severe complications—were significantly more favourable in the late group. Furthermore, there was a notable tendency for patients in the late group to experience a decreased duration of mechanical ventilation along with reduced instances of grade 3 primary graft dysfunction. CONCLUSIONS A surgical MDT can perform double LTx safely after 20 procedures. Lung transplantation (LTx) is an established treatment option to improve the quality of life and prolong survival in selected end-stage lung disease patients who have exhausted all other therapeutic options and have a shortened life expectancy [1].