Sagittal morphometry of intervertebral spaces in subaxial cervical region of asymptomatic Chinese

• Published in: European spine journal Vol. 33; no. 10; pp. 3933 - 3940
• Main Authors: Shi, Huihong, Liu, Song, Hu, Wenjun, Chen, Jianan, Chen, Yanbo, Lin, Youxi, Liao, Nianchun, Huang, Dongsheng, Gao, Wenjie, Liang, Anjing
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.10.2024; Springer Nature B.V
• Subjects: Adult; Age; Aged; Asymptomatic; Bone surgery; Cervical Vertebrae - anatomy & histology; Cervical Vertebrae - diagnostic imaging; Cervical Vertebrae - surgery; China; East Asian People; Female; Females; Humans; Intervertebral Disc - anatomy & histology; Intervertebral Disc - diagnostic imaging; Intervertebral Disc - surgery; Lordosis - diagnostic imaging; Lordosis - surgery; Magnetic Resonance Imaging; Male; Males; Medicine; Medicine & Public Health; Middle Aged; Morphometry; Neurosurgery; Original Article; Population studies; Radiography; Surgical Orthopedics; Young Adult; China; Radiography; Sagittal cervical anatomy; Morphometry; Mismatch; Cervical spine
• ISSN: 0940-6719; 1432-0932; 1432-0932
• DOI: 10.1007/s00586-024-08462-9

Purpose This study aimed to quantify and evaluate morphology of intervertebral space between neighboring cervical units using radiographic imaging indices, to help spine surgeons when performing anterior cervical discectomy and fusion (ACDF) surgery on the Chinese population. Methods The background and imaging parameters of the subjects were assessed. Cervical lateral radiographs were employed to measure the intervertebral height (IH), intervertebral height index (IHI), and segmental lordosis (SL). Endplate parameters measurements were conducted on sagittal T2-weighted magnetic resonance imaging (MRI), including endplate sagittal diameter (ESD), and endplate concavity depth (ECD). All individuals were divided into three age groups: individuals aged 20–35 were in group A, individuals aged 36–50 were in group B, and individuals aged over 50 were in group C. A comparison of the variables was conducted among the three groups. Additionally, these radiographic parameters were also compared between males and females. Results A total of 102 individuals were included in this study. IH was greater at C6/7 than those at other segmental levels ( p  < 0.001). The largest SL values were found at C6/7, while the least were found at C3/4. The superior ESD (ESDs) and ECD (ECDs) of the intervertebral space were significantly greater than those of the inferior endplates ( p  < 0.05). The ESD and ECD values were the largest at C6/7, while the least at C3/4. Additionally, age and gender had an influence on several parameters. IH was significantly lower in group A compared to group B ( p  < 0.05) and group C ( p  < 0.05) from C3/4 level to C6/7 level. ECDs were lower in group A compared to group B ( p  < 0.05) and group C ( p  < 0.05) at each level. IH and ESD in males were generally significantly greater than those in females at all levels ( p  < 0.05). Conclusion The current study found that C6/7 had the greatest IH, SL, ESD, and ECD values in asymptomatic Chinese. SL gradually increased from C3/4 to C6/7 levels. IH and ECD were significantly associated with age. Males had greater IH and ESD values than females. These findings provide baseline information for planning for selection of anterior screws and intervertebral implants.