Nondietary therapies for celiac disease

Currently, the only available therapy for celiac disease is strict lifelong adherence to a gluten-free diet (GFD). Although safe and effective, the GFD is not ideal. It is frequently expensive, of limited nutritional value, and not readily available in many countries. Consequently, a need exists for...

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Bibliographic Details
Published inGastrointestinal endoscopy clinics of North America Vol. 22; no. 4; p. 811
Main Authors Mukherjee, Rupa, Kelly, Ciaran P, Schuppan, Detlef
Format Journal Article
LanguageEnglish
Published United States 01.10.2012
Subjects
Celiac Disease - immunology
Celiac Disease - therapy
Humans
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Summary:Currently, the only available therapy for celiac disease is strict lifelong adherence to a gluten-free diet (GFD). Although safe and effective, the GFD is not ideal. It is frequently expensive, of limited nutritional value, and not readily available in many countries. Consequently, a need exists for novel, nondietary therapies for celiac disease. Based on the current understanding of celiac disease pathogenesis, several potential targets of therapeutic intervention exist. These novel strategies provide promise of alternative, adjunctive treatment options but also raise important questions regarding safety, efficacy, and monitoring of long-term treatment effect.
ISSN:1558-1950
DOI:10.1016/j.giec.2012.09.001