Safety profile and technical success of narrow window CT-guided percutaneous biopsy with blunt needle approach in the abdomen and pelvis

• Published in: European radiology Vol. 34; no. 4; pp. 2364 - 2373
• Main Authors: Rigiroli, Francesca, Camacho, Andrés, Chung, Andrew, Andrabi, Syed Yasir, Brook, Alexander, Siewert, Bettina, Ahmed, Muneeb, Brook, Olga R.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.04.2024; Springer Nature B.V
• Subjects: Abdomen; Abdomen - diagnostic imaging; Aged; Biopsy; Computed tomography; Diagnostic Radiology; Female; Humans; Image-Guided Biopsy - methods; Imaging; Internal Medicine; Interventional; Interventional Radiology; Medicine; Medicine & Public Health; Middle Aged; Neuroradiology; Pelvis; Pelvis - diagnostic imaging; Placement; Radiology; Retrospective Studies; Safety; Success; Tomography, X-Ray Computed - methods; Ultrasound; Fiducial markers; Image-guided biopsy; Biopsy; Interventional radiology
• ISSN: 1432-1084; 0938-7994; 1432-1084
• DOI: 10.1007/s00330-023-10231-z

Objective To assess success and safety of CT-guided procedures with narrow window access for biopsy. Methods Three hundred ninety-six consecutive patients undergoing abdominal or pelvic CT-guided biopsy or fiducial placement between 01/2015 and 12/2018 were included (183 women, mean age 63 ± 14 years). Procedures were classified into “wide window” (width of the needle path between structures > 15 mm) and “narrow window” (≤ 15 mm) based on intraprocedural images. Clinical information, complications, technical and clinical success, and outcomes were collected. The blunt needle approach is preferred by our interventional radiology team for narrow window access. Results There were 323 (81.5%) wide window procedures and 73 (18.5%) narrow window procedures with blunt needle approach. The median depth for the narrow window group was greater (97 mm, interquartile range (IQR) 82–113 mm) compared to the wide window group (84 mm, IQR 60–106 mm); p  = 0.0017. Technical success was reached in 100% (73/73) of the narrow window and 99.7% (322/323) of the wide window procedures. There was no difference in clinical success rate between the two groups (narrow: 86.4%, 57/66; wide: 89.5%, 265/296; p  = 0.46). There was no difference in immediate complication rate (narrow: 1.3%, 1/73; wide: 1.2%, 4/323; p  = 0.73) or delayed complication rate (narrow: 1.3%, 1/73; wide: 0.6%, 1/323; p  = 0.50). Conclusion Narrow window (< 15 mm) access biopsy and fiducial placement with blunt needle approach under CT guidance is safe and successful. Clinical relevance statement CT-guided biopsy and fiducial placement can be performed through narrow window access of less than 15 mm utilizing the blunt-tip technique. Key Points • A narrow window for CT-guided abdominal and pelvic biopsies and fiducial placements was considered when width of the needle path between vital structures was ≤ 15 mm. • Seventy-three biopsies and fiducial placements performed through a narrow window with blunt needle approach had a similar rate of technical and clinical success and complications compared to 323 procedures performed through a wide window approach, with traditional approach (> 15 mm). • This study confirmed the safety of the CT-guided percutaneous procedures through < 15 mm window with blunt-tip technique.