Changes in spinal sagittal balance after a new osteoporotic vertebral compression fracture

• Published in: Osteoporosis international Vol. 35; no. 4; pp. 645 - 651
• Main Authors: Yokoyama, Kunio, Ikeda, Naokado, Tanaka, Hidekazu, Ito, Yutaka, Sugie, Akira, Yamada, Makoto, Wanibuchi, Masahiko, Kawanishi, Masahiro
• Format: Journal Article
• Language: English
• Published: London Springer London 01.04.2024; Springer Nature B.V
• Subjects: Compression; Endocrinology; Fractures; Longitudinal studies; Medicine; Medicine & Public Health; Original Article; Orthopedics; Osteoporosis; Radiography; Rheumatology; Spine (lumbar); Stenosis; Vertebrae; Osteoporotic vertebral fracture; Total spinal sagittal balance; Sagittal vertical axis; Longitudinal study
• ISSN: 0937-941X; 1433-2965; 1433-2965
• DOI: 10.1007/s00198-023-06976-4

Summary We conduct a longitudinal study to examine how new VCF alter spinal sagittal balance. New VCF increased SVA by an average of 2.8 cm. Sagittal balance deteriorates as a VCF develops in the lower lumbar spine. A new fracture below L1 increased the relative risk of a deterioration of sagittal balance 2.9-fold compared to one above Th12. Purpose Studies on the relationship between osteoporotic vertebral fractures and spinal sagittal balance have all been limited to cross-sectional studies. The aim of this study is to conduct a longitudinal study to examine how new vertebral compression fracture (VCF) alter spinal sagittal balance. Methods Subjects were patients undergoing periodic examinations after treatment of a vertebral fracture or lumbar spinal canal stenosis. Forty patients who developed a new VCF were included in this study. Full-spine standing radiographs were compared before and after the fracture to examine changes in spinopelvic parameters and factors determining the changes in sagittal balance. Results The mean age of the patients was 79.0 years. The mean interval between pre- and post-fracture radiographs was 22.7 months, and the mean time between development of a fracture and post-fracture radiographs was 4.6 months. After a fracture, sagittal vertical axis (SVA) increased an average of 2.78 cm and spino-sacral angle (SSA) decreased an average of 5.3°. Both ⊿SVA and ⊿SSA were not related to pre-fracture parameters. The wedge angle of the fractured vertebra was not related to changes in sagittal balance. ⊿SVA increased markedly in patients with a fracture of the lower lumbar vertebrae. receiver operating characteristic analysis revealed that the relative risk of a deterioration of sagittal balance was 2.9 times higher for a new fracture below L1 than for a fracture above Th12. Conclusion New VCF increased SVA by an average of 2.8 cm. Sagittal balance deteriorates as a new fracture develops in the lower lumbar spine. Early intervention in osteoporosis is vital for the elderly.