Polymorphisms in nanog are associated with oral leukoplakia: case–control study

• Published in: Odontology Vol. 113; no. 3; pp. 1263 - 1268
• Main Authors: Michels, Arieli Carini, Scheifer, Suelen Teixeira, Tiboni, Fernanda, Modolo, Filipe, dos Santos, Emanuela Carla, Scariot, Rafaela, Aguiar, Maria Cassia Ferreira, Ignácio, Sergio Aparecido, de Noronha, Lucia, Marins, Mariana Hornung, Jham, Bruno Correia, de Souza, Cleber Machado, Johann, Aline Cristina Batista Rodrigues
• Format: Journal Article
• Language: English
• Published: Singapore Springer Nature Singapore 01.07.2025; Springer Nature B.V
• Subjects: Adult; Alleles; Case-Control Studies; Dentistry; Female; Genetic Predisposition to Disease; Genotype; Genotyping; Homeodomain Proteins - genetics; Humans; Leukokeratosis; Leukoplakia, Oral - genetics; Male; Medicine; Middle Aged; Nanog Homeobox Protein - genetics; Oral and Maxillofacial Surgery; Original Article; Polymerase chain reaction; Polymorphism, Single Nucleotide; Real-Time Polymerase Chain Reaction; Statistical analysis; Nanog homeobox protein; Embryonic stem cells; Oral leukoplakia; Genetic polymorphism

To investigate the association of NANOG polymorphisms with oral leukoplakia. In this case–control study, 68 cases of oral leukoplakia, and 21 of normal oral mucosa (control) were submitted to genotyping of tagSNPs polymorphisms: rs877716 and rs10845877 in NANOG , through real-time polymerase chain r...