On the role of polyploid giant cells in oncogenesis and tumorigenesis

This correspondence is in response to the commentary by Jinsong Liu ( https://doi.org/10.1007/s12032-023-02038-1 ) to my article “The evolutionary cancer gene network theory versus embryogenic hypotheses” published in Medical Oncology (40:114, 2023). Liu’s commentary engages head-on with the evoluti...

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Bibliographic Details
Published inMedical oncology (Northwood, London, England) Vol. 40; no. 8; p. 232
Main Author Niculescu, Vladimir F.
Format Journal Article
LanguageEnglish
Published New York Springer US 11.07.2023
Springer Nature B.V
Subjects
Carcinogenesis - genetics
Cell Transformation, Neoplastic - genetics
Embryonic Development
Female
Giant Cells
Hematology
Humans
Internal Medicine
Letter to the Editor
Medicine
Medicine & Public Health
Neoplasms - genetics
Oncology
Pathology
Polyploidy
Pregnancy
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Summary:This correspondence is in response to the commentary by Jinsong Liu ( https://doi.org/10.1007/s12032-023-02038-1 ) to my article “The evolutionary cancer gene network theory versus embryogenic hypotheses” published in Medical Oncology (40:114, 2023). Liu’s commentary engages head-on with the evolutionary cancer genome theory and defends his more histopathologically-embryogenically oriented theory of 2020. The dispute revolves, among other things, around the role of polyploid giant MGRS/PGCCs structures in oncogenesis and tumorigenesis.
Bibliography:SourceType-Other Sources-1
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ObjectType-Correspondence-1
ObjectType-Commentary-2
ISSN:1559-131X
1357-0560
1559-131X
DOI:10.1007/s12032-023-02089-4