Outcome evaluation of patients with limited brain metastasis from malignant melanoma, treated with surgery, radiation therapy and targeted therapy

Highlights • To investigate outcome results for brain metastases from melanoma • Survival was influenced by GPA score and number of metastases • No neurological deficit, major complication or CSF leakage reported • One year OS was 47% with a median of 11.8 months of actuarial survival.

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Bibliographic Details
Published inWorld neurosurgery Vol. 105; pp. 184 - 190
Main Authors Pessina, Federico, MD, Navarria, Pierina, MD, Tomatis, Stefano, MSc, Cozzi, Luca, PhD, Franzese, Ciro, MD, Di Guardo, Lorenza, MD, Ascolese, Anna Maria, MD, Reggiori, Giacomo, MSc, Franceschini, Davide, MD, Del Vecchio, Michele, MD, Bello, Lorenzo, MD, Marta Scorsetti, MD
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.09.2017
Subjects
Adult
Aged
Aged, 80 and over
Brain metastases
Brain Neoplasms - diagnostic imaging
Brain Neoplasms - secondary
Brain Neoplasms - therapy
Combined Modality Therapy - methods
Female
Humans
Karnofsky Performance Status
Local treatments
Magnetic Resonance Imaging
Male
Melanoma
Melanoma - pathology
Middle Aged
Neurosurgery
Radiosurgery
Radiosurgery - methods
Retrospective Studies
Surgical resection
Treatment Outcome
melanoma
radiosurgery
local treatments
surgical resection
brain metastases
RT
OS
MRI
WBRT
CI
Melanoma
Radiosurgery
Local treatments
Surgical resection
Brain metastases
BM
HSRS
BDP
KPS
SRS
LC
GPA
MBM
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Summary:Highlights • To investigate outcome results for brain metastases from melanoma • Survival was influenced by GPA score and number of metastases • No neurological deficit, major complication or CSF leakage reported • One year OS was 47% with a median of 11.8 months of actuarial survival.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1878-8750
1878-8769
DOI:10.1016/j.wneu.2017.05.131